Has the growing political inclusion of women, Indigenous peoples, and Afrodescendants in Latin American legislatures led to policy agendas that promote greater equality and justice for these groups? To answer this question, Making Substantive Representation analyses an original dataset of over 40,000 bills combined with qualitative interviews with legislators to systematically compare the politics of representation in Colombia, Ecuador, and Peru. This book explores under what conditions political inclusion in formal political office leads to substantive representation on political agendas, and importantly what types of historically marginalized interests are most likely to get political traction, and why. Moreover, this study considers the representation of intersectional interests – the political interests of those that are multiply marginalized – and the degree to which we see intersectional politics in today’s Latin American parliaments. It asks, for example, when do we see support for intersectional issues such as the rights of domestic workers – a workforce that is largely Indigenous and Afrodescendant and 95% female? And, which politicians are most willing to work across the boundaries of identity to support the political interests of multiple marginalized groups? By studying women, Indigenous peoples, and Afrodescendants together and in comparison, this book offer a sweeping assessment of the legislative politics of inclusion in Latin American since democratization. Moreover, it offers a fresh theoretical framework for applying intersectionality to legislative processes. While far from a utopia, and rife with continuing inequalities, the inclusion of more women, Indigenous peoples and Afrodescendants among the ranks of Latin American politicians has led to significantly greater representation of issues important to these groups on political agendas. But the paths to substantive representation have not been the same for each of these groups, and intersectional coalition building has been the exception, rather than the rule.