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Initiated by the Robert N. Butler Columbia Aging Center, the University Seminar on the Future of Aging Research has as its mission to provide an interactive interdisciplinary forum for scientists to engage with one another, to generate new ideas and new methods, and to stimulate new approaches to the science of aging. The format emphasizes dynamic exchanges and dialogue, catalyzed by brief presentations of new work by CU/CUMC researchers. Discussions are sparked by leaders in complimentary areas spanning context, individual, and organismal/biological perspectives.

Jennifer Manly

Brandon Pearson

Kavita Sivaramakrishnan

Rachel Farber

Meeting Schedule

09/18/2023 Faculty House, Columbia University
5:00 PM
Zebrafish as a translational genomics model for neuroregeneration and its implications in age-related neurodegeneration
Caghan Kizil, Taub Institute


We hypothesize that age- and pathology-related reduction in neurogenesis might be a culprit of the etiology of Alzheimer’s disease. Since neurogenesis relates to the brain resilience, restoring healthy levels of neurogenesis could have beneficial effects healthy aging. Using zebrafish, mouse, and novel 3D human neurogenesis assay systems as models to investigate the vertebrate neural stem cells, which we believe pose a unique hope to bring back lost neurons or strengthen brain wiring, we aim to find ways to restore brain function in AD through enhancing neurogenesis and neural regeneration.

12/04/2023 Faculty House, Columbia University
5:00 PM